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UnhideWhenUsed = "false" Name = "Light Grid Accent 4"

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UnhideWhenUsed = "false" Name = "O'rta Grid 1 Urg'u 4"

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UnhideWhenUsed = "false" Name = "Light List Accent 5"

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UnhideWhenUsed = "false" Name = "Dark List Accent 5"

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UnhideWhenUsed = "false" Name = "Light Shading Accent 6"

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UnhideWhenUsed = "false" Name = "Light List Accent 6"

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UnhideWhenUsed = "false" Name = "Light Grid Accent 6"

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UnhideWhenUsed = "false" Name = "Medium Shading 1 Accent 6"

<w: LsdException Locked = "false" Priority = "64" SemiHidden = "false"

UnhideWhenUsed = "false" Name = "Medium Shading 2 Accent 6"

<w: LsdException Locked = "false" Priority = "65" SemiHidden = "false"

UnhideWhenUsed = "false" Name = "O'rta ro'yxat 1 Urg'u 6"

<w: LsdException Locked = "false" Priority = "66" SemiHidden = "false"

UnhideWhenUsed = "false" Name = "O'rta ro'yxat 2 Accent 6"

<w: LsdException Locked = "false" Priority = "67" SemiHidden = "false"

UnhideWhenUsed = "false" Name = "O'rta Grid 1 Accent 6"

<w: LsdException Locked = "false" Priority = "68" SemiHidden = "false"

UnhideWhenUsed = "false" Name = "Medium Grid 2 Accent 6"

<w: LsdException Locked = "false" Priority = "69" SemiHidden = "false"

UnhideWhenUsed = "false" Name = "Medium Grid 3 Accent 6"

<w: LsdException Locked = "false" Priority = "70" SemiHidden = "false"

UnhideWhenUsed = "false" Name = "Dark List Accent 6"

<w: LsdException Locked = "false" Priority = "71" SemiHidden = "false"

UnhideWhenUsed = "false" Name = "Colorful Shading Accent 6"

<w: LsdException Locked = "false" Priority = "72" SemiHidden = "false"

UnhideWhenUsed = "false" Name = "Rangli ro'yxat 6-aksent"

<w: LsdException Locked = "false" Priority = "73" SemiHidden = "false"

UnhideWhenUsed = "false" Name = "Colorful Grid Accent 6"

<w: LsdException Locked = "false" Priority = "19" SemiHidden = "false"

UnhideWhenUsed = "false" QFormat = "true" Name = "Nozik urg'u"

<w: LsdException Locked = "false" Priority = "21" SemiHidden = "false"

UnhideWhenUsed = "false" QFormat = "true" Name = "Shiddatli urg'u"

<w: LsdException Locked = "false" Priority = "31" SemiHidden = "false"

UnhideWhenUsed = "false" QFormat = "true" Name = "Nozik ma'lumotnoma"

<w: LsdException Locked = "false" Priority = "32" SemiHidden = "false"

UnhideWhenUsed = "false" QFormat = "true" Name = "Intensiv Reference"

<w: LsdException Locked = "false" Priority = "33" SemiHidden = "false"

UnhideWhenUsed = "false" QFormat = "true" Name = "Kitob nomi"

Qonda endotoksinlar borligi endotoksemiya deb ataladi. Ushbu toksinlar, odatda, otning ichaklarida ichak devorlarini buzgan va qon oqimiga tushgan ba'zi turdagi bakteriyalar mavjudligidan kelib chiqadi. Agar tezda davolanmasa, endotoksemiya shok, laminit va o'limga olib kelishi mumkin. Bu holat kattalardagi otlarda ham, yangi tug'ilgan bolalarda ham kuzatiladi.

Alomatlar

Yuqorida aytib o'tilganidek, endotoksemiya shokka, aniqrog'i endotoksik shokka olib kelishi mumkin. Bu o'ta xavfli holat bo'lib, tezda yomonlashuvga olib keladi va agar davolanish darhol boshlanmasa o'limga olib keladi. Ushbu holatning belgilari quyidagilarni o'z ichiga oladi.

  • Depressiya
  • Letargiya
  • Suvsizlanish
  • Anoreksiya
  • O'tkir diareya
  • Pulsning ko'tarilishi (ya'ni daqiqada 80 martadan ortiq)
  • To'q binafsha rangli shilliq pardalar
  • Kolikaga o'xshash alomatlar (masalan, qorin og'rig'i, shishiradi, gaz)
  • Isitma, keyin g'ayritabiiy past harorat

Kasallik o'sib borishi bilan otda laminit paydo bo'lishi mumkin, bu og'riqli va zaiflashtiruvchi tuyoq holati bo'lib, tuyoq devori va tuyoq ichidagi suyak ajralib chiqadi.

Sababi

Endotoksemiyaning sababi gram-manfiy bakteriyalarning hujayra devorlarida mavjud bo'lgan lipopolisaxarid (LPS) deb ataladigan toksindir. Gram-manfiy bakteriyalarning ayrim turlari tabiiy ravishda ichak florasida bo'ladi va hech qanday zarar etkazmaydi, agar ot boshqa biron sababga ko'ra kasal bo'lib qolmasa va bu bakteriyalar haddan tashqari ko'payib, keyin ichak devorlarini buzib, qon oqimiga kirsa. Ushbu bakteriyalar nobud bo'lgach, ularning hujayra devorlari yorilib, LPS ni qon oqimiga chiqarib yuboradi va endotoksemiya keltirib chiqaradi. E. coli, Salmonella va Enterobacter endotoksemiyani keltirib chiqaradigan oddiy grammusbat bakteriyalardir.

Endotoksemiya rivojlanishiga olib kelishi mumkin bo'lgan ayrim taqiqlangan holatlarga quyidagilar kiradi.

  • Ichakdagi shilliq to'siqning shikastlanishi
  • Ingichka ichakning yallig'lanishi
  • Buralgan ichak
  • Kolit (stress tufayli kelib chiqqan og'ir ichak kasalligi)
  • O'tkir metrit (yuqumli kasallik tufayli bachadonning kuchli yallig'lanishi, odatda ushlanib qolgan platsentadan)
  • Kichkintoylarda kindik infektsiyasi
  • Kichkintoylarda og'iz suti etishmovchiligi

Tashxis

Otlarda endotoksemiya rivojlanib, boshqa jiddiy kasallikka chalinadi va bu hayvonlar allaqachon kasal bo'lib, kasalxonada yotishgan. Endotoksemiya klinik belgilar va ba'zan ot qonining bakterial madaniyati bilan aniqlanadi.

Davolash

Endotoksemiya holatlarida otlar tezda davolanishi kerak, natijada u muvaffaqiyatga erishishi mumkin. Davolash va qo'llab-quvvatlovchi bir necha kurslar mavjud, shu jumladan intensiv antibiotiklar, hidratsiyani saqlab turish va yurak-qon tomir tizimini qo'llab-quvvatlashga yordam beradigan IV suyuqlik terapiyasi va steroid bo'lmagan yallig'lanishga qarshi dori (NSAID), masalan, fluniksin meglumin (Banamin). otning og'rig'iga yordam beradi, yallig'lanishni nazorat qiladi va endotoksinga qarshi kurashadi. Ba'zida plazma quyish ham qo'llaniladi.

Yashash va boshqarish

Endotoksemiya o'ta xavfli holat bo'lib, hatto tajovuzkor davolanadigan holatlar ham tiklanmasligi mumkin. Bundan tashqari, endotoksemiya zaiflashtiradigan laminit (tuyoq yallig'lanishi) kabi boshqa muammolarni keltirib chiqarishi mumkin. Endotoksemiyaning har qanday holatida prognoz juda himoyalangan.

Tavsiya: